High creatinine suggests that there may be impaired renal function, and the maintenance in daily life mainly includes the following: 1, reasonable adjustment of diet, requiring low-salt, high-quality protein diet, and controlling fat intake; 2, avoiding infections and exertion, and combining work and rest, you can exercise, but you can not go to crowded places, to prevent respiratory and urinary tract infections; 3, even if there are no symptoms such as headache, dizziness, etc., it is important to Attention to regular blood pressure monitoring; 4, strive to reduce urine protein within 1g / d; 5, life as far as possible to prevent the occurrence of blood volume insufficiency, such as vomiting, diarrhea, sweating and excessive diuresis, etc.; 6, timely relief of the urinary tract of the mechanical obstruction and neurogenic bladder; 7, prohibit the use of drugs and chemicals with nephrotoxicity; 8, patients with primary glomerular disease should be actively controlled.