The possible causes of muscle pain on both sides of the spine include soft tissue lesions, spinal diseases, and occupational lesions of the spine. 1. Soft tissue lesions: mainly because of the patient’s long-term poor posture of the spine, such as long time to maintain a sitting or standing posture, may also be the local cold, resulting in myofasciitis, muscle strain, etc., may appear on both sides of the spine muscle pain symptoms. 2. Spinal diseases: such as lumbar disc herniation, cervical spondylosis, thoracic disc herniation, etc., mainly due to the herniation of the nucleus pulposus compresses and stimulates the muscles and soft tissues around the spine, and the muscles, fascia, and soft tissues are stimulated and caused by the muscle pain on both sides of the spine. 3. Occupational lesions of the spine: mainly refers to the lesions on the vertebrae of the spine, such as bone tumors, due to the invasion of tumor lesions into the spine, the muscles and soft tissues around the spine produce pressure and invasion, so there will be muscle pain on both sides of the spine. There may be other reasons for muscle pain on both sides of the spine, so it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.