If a man or a woman stays up late for a long time during pregnancy preparation, this may affect the quality of sperm, which may lead to a decrease in fertilization ability or cause a pre-miscarriage or even spontaneous abortion after pregnancy due to poor embryo quality. This is why it is recommended that both men and women should not stay up late and quit smoking and drinking during the preparation period, and must take regular rest and relaxation. Women also need to take folic acid during pregnancy preparation to prevent fetal neurovascular malformations. Although men do not need to take folic acid, they need to eat a healthy diet and get enough sleep so that the sperm quality can be optimal and the embryo can grow and develop normally after pregnancy.