Prolonged unilateral chewing can easily lead to problems such as uneven wear and tear of teeth, temporomandibular joint disorders, and asymmetry of masticatory muscles, as follows. 1. Uneven wear and tear of teeth: long time unilateral chewing will lead to serious wear and tear of teeth on the chewing side, which may develop into caries, periodontal disease, loose teeth and other diseases with time. 2. Temporomandibular joint disease: unilateral chewing will lead to fatigue of the joints on one side, which will produce strain over time. In addition, because of uneven wear of teeth, upper and lower dentition may lose stable occlusal relationship, which will also lead to temporomandibular joint disorders. 3. Chewing muscle asymmetry: The chewing muscle on one side of unilateral chewing will be fuller than the opposite side, which will cause visual asymmetry of the face. If any of the above symptoms occur, it is recommended to go to the hospital in time.