Cranial repair is a common neurosurgical procedure to repair the skull in response to traumatic brain injury resulting in a skull defect. Patients with cranial defects often have a heavy burden of insecurity and can cause syndromes such as headache, dizziness, and fear of vibration. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. In order to restore the cranial cavity confinement, keep the physiological intracranial pressure stable and reduce the cranial defect syndrome. In order to restore the cranial cavity, keep the physiological intracranial pressure stable, and reduce the cranial defect syndrome, cranial repair should be performed for cranial defects with a diameter of 3 cm or more without muscle coverage and without contraindications. For children with cranial defects, generally speaking, cranial repair is possible after 3 years of age if cranial defects occur. Restoring the integrity of the cranial cavity can improve brain tissue development and promote neurological recovery. Currently, polyetheretherketone PEEK is an ideal material with excellent performance. It has excellent biointegration properties and is ideal for pediatric patients with cranial defects to restore cranial growth and development. In fact, not only for pediatric patients, but also for adult patients, this advanced peek material also possesses great advantages in terms of complex shaping, excellent mechanical properties, good defensive properties, and high postoperative comfort, gradually gaining the latest trend in cranial repair materials.