Dry and cracked corners of the mouth is usually a sign of infectious keratitis. Infectious stomatitis is characterized by dryness and cracking of the corners of the mouth, with congestion, redness and swelling in the corners of the mouth area, or purulent secretions exuding from the mouth, usually resulting in viral, fungal and possibly bacterial infections, the most common of which is Candida stomatitis. For candida keratitis, anti-candida drugs such as mycophenolate and fluconazole can be used. Also common is herpetic keratitis, which requires antiviral medications such as 3% acyclovir ointment, alpha interferon topical application, or oral antiviral medications. There are also bacterial stomatitis, you can use chloramphenicol, gentamycin ointment, or you can take oral norfloxacin, etc., which can effectively fight bacterial infection.