Spinal pain in the center of the back can be caused by the following reasons: first, osteoporosis of the spine, osteoporosis can lead to pain in the spine, which should be diagnosed and treated early with spinal X-rays, CT and blood tests. Second, tumors of the spine, tumors or metastases of the spine can also have bone pain in the spine, then it is necessary to check the spine MRI, CT and blood tests for early diagnosis and early treatment. Third, tuberculosis of the spine, tuberculosis of the spine can also have chronic pain in the bones of the spine, which can be accompanied by systemic symptoms, such as low fever, weight loss or loss of appetite, which requires blood tests to identify the pathogenic bacteria, as well as X-rays, CT and MRI of the spine for early diagnosis and treatment.