If the fever does not go down when you take antipyretic drugs, you need to look at the current body temperature. If the temperature is just below 38℃, it is usually not accompanied by obvious discomfort, and the fever does not go down at this time, you can continue to observe and do not need to do further treatment. If the fever reaches 38.5℃ or higher at this time, or if it is accompanied by a particularly pronounced headache, general muscle aches and pains, or even a fear of cold, you can take antipyretic drugs at this time, such as ibuprofen or acetaminophen again. If you are in the hospital, you can decide whether to take blood cultures and routine blood tests for further diagnosis of the cause of the disease. If the symptoms accompanying the fever are obvious and the fever is recurrent, and the associated infection and toxic symptoms are heavy, glucocorticoids can also be used to control the inflammatory response, and the patient’s fever will gradually return to the normal range with the use of glucocorticoids.