Blistering of the tongue can be caused by recurrent mouth ulcers, herpes and traumatic ulcers, which can be relieved by taking ulcer medications, antiviral medications and applying pain relieving gels. 1. Recurrent mouth ulcers: Recurrent mouth ulcers can also lead to blistering of the tongue and pain when it moves. The patient can take cediriodine tablets as prescribed by the doctor for relief, and should reduce the stimulation of spicy food. 2. Herpes: Herpes virus infection can also cause blistering and pain on the tongue, which can be relieved by using antiviral drugs such as acyclovir tablets and valacyclovir hydrochloride. 3. Traumatic ulcers: traumatic ulcers, such as bites, eating too hot food or being hit by external forces, can also lead to tongue blistering pain, you can follow the doctor’s instructions to apply lincomycin lidocaine gel and other pain relieving anti-inflammatory drugs for relief. When the patient appeared tongue blisters move a painful situation, should be timely to the regular hospital for examination and treatment, drugs should also be taken under the guidance of the doctor.