Esophagogastric mucosal ectasia is a disease in which the gastric mucosa appears in the esophagus, causing a series of clinical symptoms or no obvious clinical manifestations, mostly related to congenital developmental abnormalities. Common manifestations Generally no clinical manifestations, a few patients may develop reflux esophagitis, which is caused by gastric acid secretion from ectopic gastric mucosa, such as retrosternal pain, pharyngeal discomfort, foreign body sensation in swallowing, nausea, vomiting, etc. In severe cases, ulcers may appear, leading to bleeding, stenosis, perforation or sinus tract formation in the neck, and in rare cases, cancer may occur. If it causes complications such as esophageal ulcer, bleeding or GERD, acid suppression therapy is recommended, and oral proton pump inhibitors should be taken as prescribed by the doctor; 3, if the effect of acid suppression therapy is poor, symptoms are frequent, or if you are worried about the possibility of cancer, endoscopic treatment can be performed, and endoscopic mucosal dissection is feasible if necessary. If necessary, endoscopic mucosal dissection can be performed. The prognosis is better with active treatment. Patients are advised to maintain a relaxed mood to avoid emotional stimulation, eat reasonably, stop smoking and drinking, avoid spicy and stimulating food to avoid stimulating the gastric mucosa, and strengthen monitoring and regular review.