Schizophrenia is a serious chronic mental illness with high recurrence and a tendency to mental decline. However, many patients do not receive timely and proper treatment. Because patients are in denial when schizophrenia strikes, relatives do not allow patients to seek timely medical care due to lack of understanding of schizophrenia or the stigma of the disease. Therefore, most patients with schizophrenia are not treated formally, which seriously affects the prognosis. First: The first episode of the disease is the best and most critical period for treatment. Patients with schizophrenia who have been ill for less than 2 years and have not undergone systematic treatment are called first-episode. Medical practice shows that timely, regular, and systematic treatment of the first episode is crucial to the prognosis of schizophrenia! At the onset of schizophrenia, the dopamine and glutamine systems in the brain are hyperactive, which can have toxic effects on brain neurons and eventually lead to loss of neuronal function and even cell death. The decline of neuronal function is the main reason for the chronicity of the disease, loss of social function and impaired mental function in patients. Therefore, the earlier the treatment, the less neurological impairment. If the patient is diagnosed in time and receives timely and effective treatment, he or she has the best chance of recovery and the best long-term prognosis. Once schizophrenia is diagnosed, regular medication should be administered immediately. Third: Due to the side effects of medication, the rejection of medication by patients and relatives, and the lack of understanding of the disease, patients often do not take their medication regularly and are eager to reduce or stop their medication, resulting in recurrence of the disease. Therefore, long-term maintenance treatment is recommended. How long do I need to maintain treatment? If the disease is stable, most experts believe that it is necessary to adhere to the first episode for about 5 years, at least not less than 3 years. Fourth: Psychological intervention After the disease is stabilized, psychological intervention is used to help the recovery of the disease and improve the compliance with treatment.