Valsartan and indapamide two antihypertensive drugs have their own merits, in the doctor’s guidance under the standardization of use is the best. 1. Valsartan: is an angiotensin II receptor inhibitor, inhibit vasoconstriction, so as to play a role in lowering blood pressure, and the effect of lowering blood pressure can be sustained for more than 24 hours, on the mild, moderate essential hypertension has a good therapeutic effect, common side effects are dizziness, headache, dry cough and other symptoms, allergy to valsartan, liver insufficiency, pregnancy, patients are prohibited to take. 2. Indapamide: indapamide is a sulfonamide derivative with an indole ring, with diuretic and calcium channel blocking effect, oral absorption is relatively fast, and completely independent of the influence of food, a few patients may have diarrhea, headache, upright hypotension symptoms, allergy to sulfonamide, renal insufficiency, hepatic encephalopathy, hypokalemia patients are contraindicated. Drugs should be taken under the guidance of a doctor and selected according to their own situation, patients should not use blindly without authorization to avoid adverse consequences.