Chronic hepatitis B virus infection, if in the immune tolerance period, that is, chronic hepatitis B virus carriers, can be normal pregnancy, but need to pay attention to close prenatal examination, and mother-to-child blocking to prevent the child is infected. If the liver function is not normal, it is safer to actively receive regular treatment, wait for the viral replication index to turn negative or the replication capacity to decrease, observe the stability of the disease after stopping the medication, and have normal liver function for more than six months to get pregnant. If short-term antiviral treatment does not achieve the above goals, it is necessary to choose the best time and the method with the least impact on the fetus under the guidance of a doctor.