The severe vulvar itching is mainly due to vaginal inflammation, such as the most common clinical Candida infection, trichomonas vaginitis, and mycoplasma and chlamydia infections, which can lead to vulvar itching. It is recommended to clinically exclude vulvar itching caused by vulvar eczema, and also exclude vulvar itching caused by vulvar dystrophy and sclerosing moss. Therefore, it is recommended to do a detailed gynecological examination, and do routine tests of the leukorrhea, if necessary, can do mycoplasma, chlamydia examination, according to the results of laboratory tests and then give targeted treatment. For vulvar dystrophy, it is recommended to use progesterone ointment and dermatophyte alternately applied to the vulva. For those who are not well treated with medication, surgery is recommended.