Whether patients with urethritis should choose cephalosporins or azithromycin for treatment depends on what the anti-infection pathogen is. If the infection is chlamydia, mycoplasma, it is recommended to choose azithromycin will be more effective than cephalosporins. And if the infection is gonococcus, it is recommended to prefer 3rd generation cephalosporins such as cefoperazone for UTI treatment. If it is some common ordinary bacteria, such as staphylococcus, E. coli, streptococcus and so on, you can choose cephalosporin drugs or azithromycin for treatment. The choice of anti-infective drugs for urethritis should be based on the type of pathogen of the infection, if it is a fungal infection to choose antifungal drugs, such as fluconazole, voriconazole and so on. If you consider anaerobic infection, choose drugs that are effective in treating anaerobic bacteria, such as metronidazole and tinidazole. If multiple pathogens are considered, a combination of anti-infective drugs may also be used.