An increase in B lymphocytes leads to an increase in CD19. Inflammation, malignant tumors, and autoimmune diseases can lead to high CD19.
CD19 is closely related to B cells undergoing proliferation, differentiation and activation, and is a CD molecule that can be expressed by B cells, also called leukocyte differentiation and formation antigen.
CD19 is commonly used in the clinical evaluation of human immune function, and a high level is mostly seen in the following diseases:
1. Inflammatory infections. Mostly caused by bacterial and viral infections, accompanied by fever, white blood cells, calcitonin and other abnormal increases.
2. malignant tumors. Acute lymphoblastic leukemia, malignant lymphoma, multiple myeloma, etc.
3. Autoimmune diseases, pernicious anemia, etc.
Due to the large impact of individual developmental differences, immunological tests also have a certain degree of error, so when there is an increase in CD19, it is recommended to continue to improve the leukocyte, neutrophil, B-cell and T-cell differentiation antigen test under the guidance of a professional physician, and combined with imaging and other means of comprehensive diagnosis and treatment.