The chickenpox vaccine does not need to be given regularly in order to maintain appropriate immunity. For a person, two chickenpox vaccinations in a lifetime will ensure that most people are free of chickenpox. If the chickenpox vaccine is given at the earliest possible age, the first shot can be given at 12-15 months of age, and the second shot needs to be given after four weeks of age. For adults, the chickenpox vaccine can be given twice, usually at least four weeks apart. The chickenpox vaccine can be given twice, and for most people, the immunity lasts a very long time and does not need to be repeated at some point in the future. The varicella vaccine is an attenuated vaccine that still has some viral activity and should not be given to people who have been taking oral immunosuppressants for a long time or who have diseases that suppress the immune system.