The heart is uncomfortable to consider may be due to nerve dysfunction, arrhythmia, myocardial ischemia and other factors, it is recommended to go to the hospital in time for a detailed examination, and then according to the doctor’s guidance and recommendations of the relevant drug treatment. 1. Neurological disorders: stay up late without rest will affect the normal nervous routine and break the natural rhythm of the heart, thus causing cardiac discomfort, generally do not need special treatment, you can use vitamin C, vitamin E and other nutrients to assist in the recovery. 2. Arrhythmia: Staying up all night will affect the cardiovascular system dysfunction, thus causing arrhythmia, resulting in heart discomfort, you can use propafenone, metoprolol and other drugs for treatment. 3. Myocardial ischemia: it is generally caused by insufficient oxygen and blood supply from coronary arteries to the myocardium, which cannot satisfy the myocardium’s shortage of oxygen and blood. Symptoms such as cardiac discomfort, arrhythmia and dyspnea will occur. Usually can use nitroglycerin, bisoprolol and other drugs under the guidance of the doctor to relieve the treatment. Usually pay more attention to the use of drugs need to follow the doctor’s instructions, maintain sufficient sleep, and good mental state, diet should be light and nutritious, and develop good habits.