The labia majora are not the same size, considering the growth and development, local stimulation, vestibular cysts or abscesses and so on. 1. Growth and development: some women may have inconsistent growth and development of labia majora on both sides due to the influence of genetic factors, so the symptom of different size of labia majora will appear, which is considered to be the normal physiological state of human body and does not need special treatment. 2. Local stimulation: If the labia majora on one side of the patient is squeezed or rubbed by external forces and stimulates the local tissue proliferation, the labia majora will also appear to be different in size. 3. Vestibular gland cyst or abscess: when the duct of the vestibular gland is blocked, it will lead to the glandular fluid can’t be discharged normally and silt in the local formation of retention cyst, which will lead to localized swelling of the labia majora, localized foreign body sensation and other discomforts, and if there is a combination of bacterial infection, then it will be developed into vestibular gland abscess, and at this time the patient will be accompanied by localized obvious redness, swelling and pain at the same time. For women whose labia majora are not the same size, it is recommended that they go to the gynecology department of a regular hospital for consultation, and then be treated under the guidance of the doctor after clarifying the cause of the disease.