At present, there is no specific treatment for liver failure in the clinic, and the main emphasis is on slowing down the speed of liver failure and actively preventing and treating complications through early diagnosis, early treatment, etiological treatment, comprehensive treatment and other measures. Liver failure is mainly caused by alcohol, drugs, viral infections and other causes of liver damage, most of which start dangerously, are difficult to treat, and have a poor recovery. Treatment is usually directed at the cause of the disease. For example, liver failure caused by hepatitis B virus infection requires antiviral treatment with nucleoside (acid) drugs, such as entecavir and tenofovir, under the supervision of a doctor. At the same time, hepatoprotective drugs (magnesium isoglycyrrhizinate, reduced glutathione), microecological regulation (such as lactulose, etc.) are applied to treat the disease, and artificial liver can be applied to treat severe cases. It is recommended that patients with liver failure, timely consultation, identify the causes, standardized treatment under the guidance of doctors, drugs should be applied under the guidance of doctors.