The causes of female non-ovulation are: First, systemic diseases, most commonly endocrine and metabolic diseases, such as severe malnutrition, hyperthyroidism, hypothyroidism, abnormal adrenocortical function, diabetes and obesity, can affect ovarian function and lead to non-ovulation. Second, the age factor, usually 1-2 years before the first menstruation, and when menopause is approaching, although there is menstruation, but most of the cycle is not ovulation. At this time, the menstrual cycle is often irregular, but rarely requires treatment, as it is a normal physiological phenomenon that women do not ovulate after a certain age. Thirdly, polycystic ovary sign, due to uncoordinated hormonal secretion in the body, makes the eggs unable to mature and many small follicles gather on the ovaries but are unable to ovulate. Patients also often have symptoms of masculinity such as hirsutism and acne, etc. The use of appropriate medication to induce ovulation can restore the ovaries to normal function.