Blisters are medically referred to as blisters. When a herpes zoster blister breaks you need to clean the contents with clean gauze, followed by a good local antiseptic wash to prevent secondary infections. Herpes zoster is a skin-damaging disease caused by reactivation of varicella zoster virus latent in the sensory ganglia of the body. It can be transmitted mainly through respiratory droplets or direct contact, but it is generally believed that herpes zoster is not mainly through exogenous infection, but is caused by reactivation of latent infection of the virus after chickenpox in infancy and childhood. After the herpes zoster blisters ruptured first need to pay attention to the lesions clean, can use sterilized gauze to clean. At the same time, pay attention to the local disinfection work, to prevent secondary bacterial infection. If the nerve pain is severe, analgesics can be used to relieve pain, such as tramadol, oxycodone and so on. In addition to this antiviral treatment is also needed, such as taking medications like acyclovir and valacyclovir. Hospitalization is required for shingles and most patients recover. Medications need to be used as prescribed by the doctor.