Level III rheumatic heart disease can last for years to decades after treatment. Survival time is usually related to the degree of progression of the disease and the promptness of treatment. Rheumatic heart disease is a heart disease caused by damage to the valves due to rheumatic inflammatory processes. It is mainly characterized by stenosis or insufficient closure of the heart valves, and common clinical symptoms include dyspnea, shortness of breath, and fatigue. It may be accompanied by arthritis, annular erythema, subcutaneous nodules and other diseases. If symptoms such as heart enlargement, cardiac decompensation, and heart failure are already present, survival time is greatly affected. If the valvular lesions are not severe, the survival time can be extended to a greater extent with aggressive drug therapy and surgery. Commonly used medications include prednisone, nifedipine, and lincomycin. Commonly used surgical procedures include heart valve repair, artificial heart valve replacement, arteriotomy and thrombectomy. Tertiary rheumatic heart disease is usually not curable, but active treatment can prolong the patient’s survival for years or even decades.