Orange peel manifestation of breast cancer refers to the appearance of epidermal edema and elevation of breast skin with obvious sinking of follicular pores, which looks like orange peel and is related to the blockage of lymphatic vessels by breast cancer. Orange peel change is one of the characteristic manifestations of breast cancer, which means that after the superficial lymphatic vessels are invaded and blocked by breast cancer cells, the obstruction of lymphatic return leads to localized dermal edema of the skin, and the hair follicles and the follicular pores are obviously sunken, and then the skin manifestation of orange peel appears. In addition to orange peel-like changes, breast cancer also has “dimple sign”, nipple overflow and other manifestations. It can invade into pectoral muscle fascia and pectoral muscle, so that the tumor is fixed and not easy to be pushed, and it can be transferred to axillary lymph nodes through lymph nodes, and it can also be distantly transferred to bones, liver and lungs. Early manifestation of breast cancer is the appearance of painless, single small nodule in unilateral breast. If a woman touches a nodule on her breast, she should go to the breast surgery department of the hospital in time to get a clear picture of the cause of the disease, so as to strive for early detection and early treatment.