Thrombin is mainly applied to various kinds of hemostasis and bleeding. In the clinic, it is mainly applied to the bleeding symptoms caused by various diseases or local trauma, and can be injected intramuscularly and applied locally with wet compresses to achieve the effect of rapid hemostasis. It can make the soluble fibrinogen in the blood become insoluble fibrin, and the blood on the surface of the lesion will coagulate rapidly, and thrombin can also act directly on the blood. At present, it has been widely used in the clinic, and can be applied to various parts, especially applied to capillary hemostasis or small vessel hemostasis. It should be noted that in clinical application, a small portion of patients may develop allergy after using thrombin, in which case the use should be stopped immediately.