1, there is epigastric pain, abdominal distension, nausea, vomiting, acid reflux, belching. Patients with discomfort such as dysphagia, painful swallowing retrosternal burning sensation, suspected esophageal, gastric and duodenal inflammation, ulcer and tumor. 2.Patients with symptoms such as vomiting blood, black stool, suspected upper gastrointestinal bleeding, patients who need to determine the presence of upper gastrointestinal bleeding, but the cause and location are unknown or patients who need endoscopic treatment to stop bleeding. 3. Patients with stomach-related systemic symptoms (such as unexplained wasting, anemia, enlarged left supraclavicular lymph nodes, etc.). 4.Patients who are suspected of having upper gastrointestinal lesions on imaging examinations (such as barium meal examination of the upper gastrointestinal tract) but fail to be diagnosed. 5.Regular review of certain upper gastrointestinal diseases (ulcer, atrophic gastritis, precancerous lesions, etc.) and evaluation of efficacy before and after drug treatment or after surgery. 6.Patients with gastric or duodenal augmentation lesions, or polyps that need to be cut (or removed) under endoscopy.