Normal human d-dimer is less than 200 micrograms / liter, pregnancy d-dimer will be elevated to the usual 2-3 times is normal, and pregnant women plasma d-dimer measured 4400 micrograms / liter, elevated to the normal about ten times, so this situation is very abnormal, should be timely medical care. Elevated d-dimer levels indicate the presence of hypercoagulability and secondary hyperfibrinolysis in the body, which is important for the diagnosis, efficacy assessment, and prognosis of thrombotic diseases. Pregnant women’s blood is already in a hypercoagulable state during pregnancy, and an elevation of 2-3 times is generally acceptable. However, if the magnitude of the elevation is relatively large, such as an elevation of about ten times, the situation should be taken seriously because the extremely elevated d-dimer in a hypercoagulable state will affect the implantation of the gestational sac or blood flow, thus affecting the blood supply to the fetus. Treatment with heparin sodium injection is required as an option under medical supervision. When the above abnormalities occur in the clinic, timely consultation and active treatment should be sought to avoid delaying the condition.