Hairy thickening of the gallbladder wall is generally a manifestation of chronic cholecystitis, chronic cholecystitis gallbladder wall thickening greater than 5mm is an indication for surgery, so thickening of 8mm requires surgery. Chronic cholecystitis is a persistent, recurrent inflammation of the gallbladder, due to the continuous stimulation of inflammation, resulting in thickening of the gallbladder wall, edema, local morphology irregularities, manifested as a thickening of the gallbladder wall roughness. In the case of chronic cholecystitis, if the gallbladder wall gradually thickens more than 5mm, if malignant changes are suspected, or if the symptoms significantly affect normal life, the indication for surgery is reached. Thickening of the gallbladder wall may also be caused by other reasons, which need to be analyzed specifically. It is recommended that the patient go to the hospital, complete other tests to determine the cause of the disease, and treat the symptoms under the guidance of the doctor.