Appendiceal mucinous cystadenoma, which is considered to be an appendiceal mucinous cyst, can be cured by timely and standardized surgical treatment, but is prone to recurrence. Appendiceal mucinous cystadenoma is mainly caused by the narrowing or obstruction of the appendiceal lumen, and the common symptoms are pain in the right lower abdomen, nausea and vomiting, and a mass in the right lower abdomen will be palpated on examination. Treatment of appendiceal mucinous cystadenoma is mainly surgical. The appendix and the cyst can be removed completely through surgery, and the spilled mucus can be removed, and part of the colon should be removed if necessary. Chemotherapy drugs, such as 5-fluorouracil, can be used to minimize the recurrence of the disease. Appendiceal mucus cysts should be promptly consulted, early detection, early treatment, and follow the doctor’s instructions to take appropriate treatment measures, and also need regular follow-up after surgery.