Will diabetes be passed on to my children?

  In clinical work, I often hear the question, “Will I pass my diabetes on to my child? This is a very realistic question, and from the perspective of eugenics, it reflects the highly responsible attitude of the questioner for the future of the child and for the quality of human beings themselves, which deserves praise.  So far, there is a lot of research data from home and abroad that shows that diabetes is hereditary. For example, in the case of identical twins, if one of the twins has type 1 diabetes, the chance of the other twin developing the disease in the future can be as high as about 50 percent. This is the most compelling epidemiological evidence that diabetes is hereditary.  In terms of the origin of life, the most important substance that makes up a living body is protein. Our epidermis, bones, internal organs, head, face, five senses, and any other kind of tissue are mainly composed of proteins. So, why do we have such a variety of different shapes and forms? This mystery is determined by the genetic information in the body, this genetic information is stored in a carrier called “genes”, it is the smallest genetic unit in the body, is able to pass on to the next generation, in the human body, there are about 40,000 such functional genes, a “gene A “gene” determines a protein, and the structure of each protein is different, which is the reason for the richness of living organisms. It governs the whole process of our life such as birth, old age, illness and reproduction.  Now, let’s go back to the previous question. Diabetes is a polygenic disease that is the result of multiple genes acting together, but whether diabetes develops or not is also influenced by environmental factors, so some individuals, although carrying a disease-causing gene, can not develop the disease if there is no suitable exogenous effect. In addition, genes are not simply passed from one to the next, so it is unlikely that all offspring will “take over” the disease causing genes from their fathers. Secondly, as mentioned above, even if the gene is “replaced”, the disease may not necessarily develop without the action of external factors. Rarely, due to the diversity of diabetes genes and ethnic differences, there is no medical way to detect diabetes by prenatal screening. This is one of the directions that medical science needs to work on in the future.