The 54u/L of AST requires lifestyle improvement along with the choice of medications such as entecavir or surgical treatments for the cause of the disease. The reference value of AAT is between 0 and 40u/L, so when the level is 54u/L, it is mildly elevated. In this case, it is necessary to improve the poor lifestyle, including maintaining a good routine, do not stay up all night, and need to avoid oily and high salt diet, quit drinking and smoking, and maintain appropriate exercise. In addition, we need to clarify the cause of the disease, if it is viral hepatitis, we need to use anti-viral replication drugs such as entecavir; if it is biliary obstruction, we need to unblock the bile duct through surgery; if it is malnutrition, cardiomyopathy, cerebrovascular disease, skeletal muscle disease, pancreatitis and other causes of transaminase elevation, we need to treat the primary disease first. It is recommended to consult a doctor for standardized diagnosis and treatment when necessary.