When swallowing saliva, one side of the throat tingles clinically with the following diseases: the first, peri-tonsillitis or peri-tonsillar abscess, which is mainly manifested as a unilateral lesion, the lesion inflammation is confined to the peri-tonsillar space, clinically you can usually see the tonsils move inward, the tonsil surface is congested, the anterior arch of the tonsils and the soft palate is locally elevated. In this case, antibiotic treatment is clinically necessary, and if an abscess forms, incision and drainage treatment is required. Secondly, some patients may have lingual-pharyngeal neuralgia, where the trigger point is stimulated when the patient swallows saliva, thus inducing a unilateral tingling sensation in the distribution area of the lingual-pharyngeal nerve, which is still very common. In conclusion, patients who experience pain on one side of the throat when swallowing saliva are advised to go to an ENT clinic for an examination to see which disease they belong to.