Fast walking ankle pain may be caused by ankle fracture, ankle osteoarthritis, ankle sprain and other reasons. 1. Ankle fracture: when there is a slight fracture of the ankle, there is no obvious pain when resting, and walking fast can lead to ankle weight-bearing increase and aggravate the displacement of the fracture, thus causing pain in the ankle area. 2. Osteoarthritis of the ankle joint: patients with osteoarthritis of the ankle joint have lesions of the articular cartilage, the joint surface is uneven, and the friction and abrasion of the articular surface during brisk walking can cause pain in the ankle area when walking. 3. Ankle sprain: after ankle sprain, the surrounding ligaments are overstretched, which may lead to ligament damage and cause pain in the ankle area when walking. Fast walking ankle pain can also be seen in the ankle ligament laxity, it is recommended to go to the hospital in time, under the guidance of professional physicians to clarify the cause of the disease, targeted treatment.