How to deal with urine protein 3+ depends on the patient’s condition, which can be seen in physiological factors such as cold stimulation or strenuous exercise, as well as pathological factors such as primary or secondary renal disease, etc. Physiological factors generally do not need to be dealt with, and some renal diseases need to be treated by applying immunosuppressants such as cyclophosphamide or glucocorticosteroids such as methylprednisolone. Urine protein is the protein excreted through the urine, healthy people’s urine protein characterization is generally negative, the appearance of urine protein 3 + for urine protein positive. Physiological factors, such as cold stimulation or strenuous exercise, can cause positive urine protein, generally do not need to be dealt with, after removing the triggers of urine protein can be turned negative. Pathological factors include primary or secondary renal disease, etc. Diagnosis of renal disease need to be examined, including urine routine, renal function, etc., according to the patient’s clinical symptoms and test results to confirm the diagnosis of the disease. Immunosuppressants such as cyclophosphamide or glucocorticoids such as methylprednisolone can be used according to the condition. Patients with urinary protein 3+ are advised to go to the hospital in time, complete the relevant examinations, make a clear diagnosis, and carry out standardized treatment under the guidance of the doctor.