Newborns armpit drowning, may be the existence of inter friction rash, should be cleaned on the armpit area, keep dry, and apply talcum powder in the affected area, when the symptoms are more obvious, can be used externally with erythromycin ointment and other drugs treatment. Parents do not pay attention to the care of newborns, armpit area sweating more, due to sweat stimulation, may lead to armpit area redness, tingling and other symptoms, should be timely cleaning of the armpit area, and keep the armpit area dry. The symptoms caused by rubella are more obvious, such as redness, swelling, inflammation, should also be used externally erythromycin ointment and other anti-inflammatory drugs to deal with the treatment, during the treatment period, the indoor temperature should be adjusted, give the child a change of cotton loose clothing, and to avoid armpit areas of skin damage. Parents should not easily give the child medication, should follow the doctor’s instructions, safe and reasonable use of topical drugs, to avoid improper use of drugs caused by adverse reactions.