Thick lining without menstruation is considered to be related to pregnancy and endocrine disorders. 1. Pregnancy: For pregnant women, if the gestation time is relatively short or the quality of the embryo is not good and spontaneous abortion occurs, the obvious gestational sac may not be found under the ultrasound or has been naturally discharged, and at this time due to the elevated level of estrogen and progesterone in the body will inhibit the function of the gonadal axis and the menstrual period will stop, resulting in the situation of a thick endothelial lining. 2. Endocrine disorders: for women with high mental stress or gynecological endocrine diseases such as polycystic ovary syndrome and premature ovarian failure, due to the abnormal endocrine function, which will lead to irregular ovulation or no ovulation, the endothelium can not be peeled off due to the lack of progesterone antagonism and the endothelium is thick and does not have a menstrual period. It is recommended to go to the gynecology department of a regular hospital, complete the relevant examinations, and then take active treatment under the guidance of the doctor after clarifying the cause of the disease.