The elimination of gout stone needs to be chosen according to the size of the gout stone, smaller gout stones can be relieved by lowering the blood uric acid, increasing the blood uric acid discharge, etc. Larger gout stones, which affect the quality of life, can be treated by surgical removal and so on. Gout stones, also known as gouty nodules, occur mainly in the middle and late stages of gout when urate precipitates in the soft tissues in the form of tiny needle-like crystals, leading to inflammation and foreign body reaction, and fibrous tissue proliferation to form nodules. Smaller nodules can be treated by medication, such as the use of benzbromarone, which promotes uric acid excretion, and allopurinol and febuxostat, which inhibit the production of uric acid for uric acid control, as well as dietary control, consumption of low-purine foods, and drinking more water to increase urination. However, if the gout stone is large, it can not be removed by medication, and may affect the joint function, compression to the nerve and affect the function of organs, can be treated by surgical incision to remove. It is recommended that patients with gout stone go to the hospital, follow the doctor’s advice to choose the appropriate treatment, the medication should be used in accordance with the doctor’s advice, do not self-medication.