Uremia, which is the complete or partial loss of the patient’s ability to concentrate urine, is characterized by polydipsia, polyuria, and the discharge of dilute urine. Uremia is divided into two categories: central uremia, and renal uremia. Central dysuria can occur at any age, with thirst, polydrinking and polyuria as the main clinical symptoms. The causes are mostly related to hypoplasia or degenerative lesions of the supraoptic nucleus of the hypothalamus or paraventricular neurons. There are also factors such as tumors, injuries, infections, and hereditary factors. Its treatment should take the cause of treatment, as well as drug treatment methods, must be clearly identified, the specific causes of central uremic syndrome, to take symptomatic use of drugs. During the period of treatment, it is necessary to avoid eating foods high in protein, fat, sodium and salt, as well as alcohol and tobacco, pay attention to rest, prevent infection, and pay attention to weight changes.