Postprandial gallbladder refers to the physiological state of the gallbladder after a person has eaten a meal. Usually the gallbladder is less full after a meal and the gallbladder excretes bile into the intestine, so the phenomenon of postprandial gallbladder is triggered. This is because clinically the secretion of bile is continuous, but the discharge of bile is intermittent with the person’s eating, usually through contraction of the smooth muscle of the gallbladder and relaxation of the sphincter of Oddi. This condition is regulated by a combination of neurological and humoral factors, such as gastrointestinal hormones, metabolites, and some drugs, among others. The duration of each bile drainage is related to the type and amount of food, and approximately 15% of bile remains stored in the gallbladder after the completion of each bile drainage phase.CCK, the main physiological stimulus for postprandial gallbladder contraction, is clinically a normal physiological state of the body and not a pathological state.