The survival time of patients with second recurrence of liver cancer is usually within 3~5 years, but some patients may be in more serious condition and their survival time may not exceed 2 years. For second recurrence of liver cancer, clinically, patients are advised to determine the corresponding treatment plan according to their recurrence location. If the recurrence is less serious and the tumor is smaller, the survival time will be longer, which will be 3~5 years. However, if the second recurrence of liver cancer is more serious and the tumor is larger, with multiple distant metastases and recurrence, radical treatment is generally ineffective, and the survival time may only be 1~2 years, or even less than one year. The specific survival time cannot be determined because there are many influencing factors, such as the degree of malignancy of the tumor, recurrence of the tumor, and the degree of effectiveness of follow-up treatment, so only a rough assessment of survival time can be made.