Tooth fistula with pus all the time is usually related to diseases such as apical periodontitis, periodontitis, periodontal cyst, etc. It can be treated with general treatment, medication, or surgery according to the cause of the disease. 1. Periapical inflammation: inflammatory reaction occurs in the periapical area, resulting in apical abscess with pus formation, and root canal treatment should be carried out as soon as possible. When combined with inflammatory infection, oral metronidazole plus cefixime is needed. 2. Periodontitis: Repeated inflammatory stimulation of the periodontium can also cause abscesses. Treatment, need to control plaque, combined with anaerobic infection, should be oral metronidazole, tinidazole, if necessary, and then combined with tetracycline, doxycycline and other drugs. When the formation of abscess, then give local injection minocycline gel, but also need to carry out systemic periodontal treatment such as cleaning, scraping, etc.. 3. Periodontal cysts: small periodontal cysts do not require special treatment, such as more serious periodontal cysts, affecting normal chewing, can be directly surgical excision. Periodontal fistula has been pus, such as the above factors, should be targeted treatment as soon as possible, but the specific treatment program is recommended to consult a doctor, the use of drugs need to comply with medical advice.