Craniosynostosis is a relatively common craniosynostosis in neurosurgery, and the age of onset of this disorder is relatively discrete. Many children may suffer from cranial defects due to car accidents, falls from height, craniotomy for craniosynostosis, and so on. Cranial defects can have many adverse effects on the human body, so cranial repair is needed in a timely manner. The cranial repair material is an important factor, and among the materials currently in clinical use, polyether ether ketone PEEK is a new polymer material with excellent performance and is becoming a new trend in cranial repair materials. The current advanced PEEK material for cranial repair is very good in shaping, and the three-dimensional reconstruction is very good in shaping. Currently, polyetheretherketone PEEK material is a very advanced cranial repair material that fully complies with national standards for human implants, and its properties are basically comparable to autologous cranial bone with excellent histocompatibility, which will not affect the growth and development of children. Moreover, our team not only adopts this advanced PEEK material, but also constantly carries out optimization design and technical innovation of the material, and also introduces the concept of cosmetic plastic surgery to refine and personalize the cosmetic treatment of factors affecting the appearance of the patient, which has achieved good results of structural integrity, functional perfection and beautiful appearance, and is widely recognized and praised by patients and their families.