Adrenocortical hyperplasia, usually referred to as congenital adrenocortical hyperplasia, is an autosomal recessive disorder, meaning that pregnancy determines whether a child will have the disorder in the future. The human adrenal gland is an endocrine organ that secretes steroid hormones. There are many steps in the synthesis of steroid hormones, and each step requires specific enzymes to catalyze the process, and depending on the type of defective enzymes, there are different types of diseases, but the clinical manifestations mainly include the following two categories: 1. Excessive androgens: Commonly found in patients with precocious puberty. If a boy develops excessive androgen secretion, it will lead to premature gonadal development, premature appearance of secondary sexual characteristics, and height in adulthood is instead inferior to that of normal children; 2. Salt loss: mainly the electrolyte balance in the body is problematic, and patients show clinical symptoms such as weight loss, loss of appetite, vomiting and dehydration, mainly hypokalemia and hyperkalemia that are difficult to correct.