Phlegm can take some drugs that are conducive to phlegm dissolution, dilution, discharge, such as aminobromine, guaiacol glyceryl ether, etc., but also nebulized inhalation of acetylcysteine and other drugs, in order to promote the discharge of phlegm; but also need to be directed at the causative organisms of the treatment, such as the use of amoxicillin, levofloxacin, and so on. Phlegm dissolving drugs are mainly used for sputum, thick and not easy to cough out, common sputum thinner guaiacol glycerol ether, can be stimulated through the bronchial secretion, in order to dilute sputum, and is conducive to sputum coughing out. Common sputum solubilizers include: Ambroxol, acetylcysteine, carbocysteine, eucalyptus-pinene enteric soft capsule, etc., which can reduce the viscosity of sputum, so as to facilitate the discharge of sputum. It can also be treated by local nebulization to dilute the sputum, such as using inhaled acetylcysteine. However, acetylcysteine should be used with caution in people with asthma. The sputum is thick and not easy to cough up, mostly related to the presence of infection, the more common is a variety of bacterial infections, need to give antibacterial treatment, can follow the doctor’s prescription empirical or according to the drug sensitivity test to reasonably select anti-bacterial drugs, such as amoxicillin, levofloxacin, cephalosporins, etc., only effective control of the infection can be expectorated from the root of expectoration, phlegm. The above drugs need to be standardized and rationally applied under the guidance of professional physicians and pharmacists. If the symptoms fail to improve or even gradually worsen, you need to consult a regular hospital in time, and cooperate with the doctor to improve the examination and standardized treatment.