Onitrazole should not be taken during breastfeeding, and if it is not possible to replace the drug by another drug for the treatment of the disease, it is recommended to stop breastfeeding and artificial feeding during the administration of the drug. Onitrazole is a third-generation nitroimidazole drug, which can be used to treat anaerobic infectious diseases such as liver abscess, periodontitis, endometritis, cellulitis, gas gangrene, etc., trichomonas infection of the reproductive tract, digestive system amoebiasis and other diseases. The drug has not been studied in relation to the use of pregnant and lactating women, so it can not be used for the treatment of the above diseases in early pregnancy and lactation. In case of breastfeeding women, it is recommended to stop breastfeeding and artificial feeding if the drug cannot be replaced by other drugs for the treatment of these diseases. It is recommended to stop using the drug in case of adverse reactions such as peripheral neuropathy, vertigo, tremor, abnormal impairment of liver function. The use of the drug is prohibited in cases of drug hypersensitivity, the presence of central nervous system diseases such as epilepsy, organ sclerosis, leukemia and other hematologic malignancies. The drug needs to be used under the supervision of a clinician.