Vitiligo can be relieved with medications, but it cannot be cured, commonly used glucocorticoid preparations, calcium-modulated phosphatase inhibitors and so on. Vitiligo is an acquired pigment loss skin and mucous membrane disease, its pathogenesis is not clear, and there are difficulties in treatment. Drugs are difficult to completely eradicate the disease, but can alleviate the symptoms. Glucocorticoid preparations are suitable for progressive lesions, commonly used are fluticasone propionate, betamethasone valerate and so on. Calcium-modulated phosphatase inhibitors are effective in recoloring the neck, face, and folds, and are suitable for both adults and children, commonly used are tacrolimus ointment, pimecrolimus cream, and so on. The specific use of the drug depends on the condition, it is recommended to follow the doctor’s instructions to use the drug, you can get a better therapeutic effect.