The normal flora in the oral cavity can maintain the dynamic balance of the oral microenvironment and usually does not require treatment if it does not cause any symptoms. If cariogenic microorganisms, such as Streptococcus pyogenes, Lactobacillus spp. and Actinobacillus spp. are present and proliferate and metabolize acid production, it will easily lead to tooth decay. In case of bacterial infection such as Porphyromonas gingivalis and Prevotella intermedia, it is related to periodontal disease. When harmful bacteria invade into the mouth, symptomatic treatment and removal of pathogenic factors are the main reasons, such as timely sulcus closure after the eruption of milk molar and permanent molar, which can effectively avoid bacterial invasion; caries can be filled with light-curing resin, glass ion, etc., to eliminate food embedding and adjust occlusion; patients with periodontal disease can undergo supragingival scaling and subgingival scraping, and periodontal surgery if necessary; coccidioidomycosis Stomatitis is based on anti-inflammatory and oral cleaning. Antibiotics can be used under the guidance of a doctor, such as compound chlorhexidine rinse, amoxicillin, ornidazole, but not all cases are suitable for the application of antibiotic drugs. In daily life, pay attention to maintaining oral hygiene, rinse your mouth after meals and brush your teeth on time. Eat a light diet, eat more fresh vegetables and fruits, eat less sweets and avoid spicy and stimulating foods. Do not use mouthwash often, so as not to destroy the role of the normal flora in the mouth. Exercise more to enhance personal fitness, do not stay up late, and seek medical treatment in a timely manner when uncomfortable symptoms appear.