Slightly enlarged mesenteric lymph nodes refer to lymph nodes in the abdominal mesentery that are enlarged due to increased local secretion of inflammatory mediators, resulting in a range of symptoms such as abdominal pain and anorexia. It is a common cause of abdominal pain in children, especially in adolescents between the ages of 10 and 18, but it is usually less severe and the symptoms gradually resolve over a period of weeks. If a child has severe abdominal pain due to enlarged mesenteric lymph nodes, abdominal CT examinations should be performed to determine the nature of the enlarged lymph nodes, the degree of adhesions between the lymph nodes and surrounding tissues, and the presence of other lesions. After detection of enlarged mesenteric lymph nodes, you can use the palm of your hand to rub the child’s stomach in a clockwise direction to slightly relieve the pain during the acute pain period.