Desensitizing needles, also known as desensitizing drugs, which are drugs applied when the body is in a variety of antigenic substances such as bacteria, viruses, pathogenic microorganisms, parasites and other allergy-mediated diseases of the immune system, also known as anti-allergy drugs, are usually divided into the following four categories: first, the commonly used clinical isoprostanes, paracetamol are desensitizing needles, also belong to the antihistamine class of drugs; second, desensitizing needles belong to the release of anti-allergic mediators of a drug, which can stabilize mast cell membranes and inhibit mast cell degranulation; third, leukotriene receptor antagonists, representative drugs are montelukast sodium, ketotifen and other drugs. It can stabilize the mast cell membrane and inhibit mast cell degranulation, such as sodium cromoglycate, ketotifen and other drugs; third, leukotriene receptor antagonists, representing drugs such as montelukast sodium, mainly used in respiratory allergy, such as the treatment of allergic asthma; fourth, antigen-antibody complexes, such as adrenaline, adrenal glucocorticoids, commonly used drugs such as dexamethasone, methylprednisolone and other drugs.