Nocturnal urination once is a normal phenomenon. Nocturnal urination is generally normal, under normal circumstances, the frequency of nocturnal urination is 0~1 times, which is a normal situation, but more than once is an abnormal situation. Patients may drink more water at night or drink more water before going to bed, which can cause urination at night, but it will not be accompanied by any self-awareness symptoms, and there will be no pain or burning, elevated body temperature, and the feeling of incomplete urination. Patients can reduce the amount of water consumed before going to bed and observe whether there is any improvement, or it may be a natural manifestation of the gradual deterioration of bladder function with age. If urination occurs once at night, no medication is needed, and regular clinical follow-up is recommended.